Microtissues®

Cancer Spheroids & 3D Tumor Models

Oncology is the largest application area for the 3D Petri Dish®. Tumor cells seeded into the non-adhesive agarose micro-mold self-assemble into uniform spheroids — 3D tumor models with the cell–cell contacts and gradients that make them more representative than flat culture, formed without scaffold or animal-derived matrix.

One pipetting step yields an array of matched spheroids, so drug-response, invasion, and immuno-oncology experiments start from consistent 3D structures. The peer-reviewed studies below cover tumor mechanics, nanoparticle delivery, drug uptake and penetration, co-culture models, and more.

Getting started: follow the step-by-step protocols for casting, seeding, and harvesting, or browse 3D Petri Dish® micro-molds for 12- and 24-well plates — $575/pack, free worldwide shipping.

135 peer-reviewed publications

Oncology

3D Bioprinted Breast Cancer‐Stroma Model with Tailored Migration‐Permissive Bioink Reveals Impact of Adipose‐Derived Stromal Cells on Cancer Cell Migration and Invasion Dynamics

Advanced Healthcare Materials · 2026 · Stecher, Sabrina, et al

Published in Advanced Healthcare Materials (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Stecher, Sabrina, ...

Oncology

Access to β-acetoxyselenides, perhydroindolones and anticancer piperidinones via blue LED-driven selenylation of unsaturated carboxamides

Scientific Reports · 2026 · Vaskevych, Alla, et al

Published in Scientific Reports (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Vaskevych, Alla, et al. Acces...

Oncology

Beyond one-size-fits-all: cancer biology shapes nanoparticle behavior

Journal of Nanobiotechnology · 2026 · Bravo, Maria, et al

Published in Journal of Nanobiotechnology (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Bravo, Maria, et al...

Oncology

Brain metastasis‐associated fibroblasts shape the tumour microenvironment to enhance cancer cell invasion

Brain Pathology · 2026 · Výmolová, Barbora, et al

Published in Brain Pathology (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Výmolová, Barbora, et al. Brain ...

Oncology

Ex vivo drug sensitivity testing predicts treatment outcomes in advanced ovarian cancer

npj Precision Oncology · 2026 · Labrosse, Kathrin B., et al

Published in npj Precision Oncology (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Labrosse, Kathrin B., et ...

Oncology

Extracellular vesicles shed by multidrug resistant cells contribute to the identification of SRC inhibitors as chemosensitizers in non-small cell lung cancer

Cancer Drug Resistance · 2026 · Polónia, Bárbara, et al

Published in Cancer Drug Resistance (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Polónia, Bárbara, et al. ...

Oncology

From Luminal to Triple Negative: 3D Spheroids Reveal Molecular and Phenotypic Differences Across Breast Cancer Subtypes

International Journal of Molecular Sciences · 2026 · Castro, Maria Miguel, et al

Published in International Journal of Molecular Sciences (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Cast...

Oncology

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

Advanced Science · 2026 · Yang, Jianqiang, et al

Published in Advanced Science (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Yang, Jianqiang, et al. GLS1 Or...

Oncology

Imidazole-2-thione derivatives as new selective anticancer agents with anti-metastatic properties: synthesis and pharmacological evaluation

Journal of Enzyme Inhibition and Medicinal Chemistry · 2026 · Golcienė, Božena, et al

Published in Journal of Enzyme Inhibition and Medicinal Chemistry (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citat...

Oncology

Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer

Science Advances · 2026 · Parikainen, Marjaana, et al

Published in Science Advances (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Parikainen, Marjaana, et al. Ja...

Oncology

Longitudinal investigation of prostate tumor spheroid proliferation with dynamic line-field optical coherence tomography

Biomedical Optics Express · 2026 · Swanson, Steph, et al

Published in Biomedical Optics Express (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Swanson, Steph, et al....

Oncology

Protocol for culture, drug treatment, and dissociation of patient-derived 3D ovarian cancer microspheroids for flow cytometry

STAR Protocols · 2026 · Haffa, Mariam, et al

Published in STAR Protocols (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Haffa, Mariam, et al. Protocol fo...

Oncology

Synthesis and anticancer evaluation of novel thioimidazole derivatives bearing a trimethoxyphenyl moiety

Scientific Reports · 2026 · Maciejewska, Natalia, et al

Published in Scientific Reports (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Maciejewska, Natalia, et al. ...

Oncology

Targeting the Hippo/YAP-TAZ pathway increases X-ray sensitivity in chondrosarcoma spheroids and is associated with autophagic disruption

Journal of Bone Oncology · 2026 · Lohberger, Birgit, et al

Published in Journal of Bone Oncology (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Lohberger, Birgit, et a...

Oncology

The Flavonoid Rutin Enhances Temozolomide Sensitivity in Glioblastoma Spheroids by Modulating Chemoresistance via PI3K/AKT, STAT3, Redox and Kynurenine Pathways, and Altering ECM Remodeling Associated with Reduced Migration

Antioxidants · 2026 · Lima, Irlã Santos, et al

Published in Antioxidants (2026), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Lima, Irlã Santos, et al. The Flavo...

Oncology

A Model of Breast Cancer Micrometastasis in a Three-Dimensional (3D) Liver Spheroid for Testing an Antimetastatic Therapy

BIO-PROTOCOL · 2025 · Nevskaya, Kseniya, et al

Published in BIO-PROTOCOL (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Nevskaya, Kseniya, et al. A Model o...

Oncology

C5aR1 Promotes Invasion, Metastasis, and Poor Prognosis in Cutaneous Squamous Cell Carcinoma

The American Journal of Pathology · 2025 · Heiskanen, Lauri, et al

Published in The American Journal of Pathology (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Heiskanen, Lau...

Oncology

Differential unfolded protein response regulation in KRAS silencing sensitive and innately resistant colorectal cancer cells

Scientific Reports · 2025 · Martins, Flávia, et al

Published in Scientific Reports (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Martins, Flávia, et al. Diffe...

Oncology

Direct transfer of multicellular tumor spheroids grown in agarose microarrays for high-throughput mass spectrometry imaging analysis

Analytical and Bioanalytical Chemistry · 2025 · Liu, Yuan, et al

Published in Analytical and Bioanalytical Chemistry (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Liu, Yuan...

Oncology

Evaluation of Photodynamic Therapy Using AuNPs@Ce6 in 3D Cultures of Triple-Negative Breast Cancer

J · 2025 · Ventura, Aveline, et al

Published in J. Multidisciplinary Science Journal (2025), this study evaluated gold nanoparticles conjugated with Chlorin e6 (AuPs@Ce6) for photodynamic therapy (PDT) against tripl...

Oncology

G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic α cells

Science Translational Medicine · 2025 · Bahl, Varun, et al

Published in Science Translational Medicine (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Bahl, Varun, et a...

Oncology

Immunostimulatory effects of IL-12 targeted pH-responsive nanoparticles in macrophage-enriched 3D immuno-spheroids in vitro model

Drug Delivery and Translational Research · 2025 · Silveira, Maria José, et al

Published in Drug Delivery and Translational Research (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Silveir...

Oncology

Improved anti-breast cancer activity through structural modification of fused pyran derivatives and mechanistic investigations

RSC Medicinal Chemistry · 2025 · Fabitha, K., et al

Published in RSC Medicinal Chemistry (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Fabitha, K., et al. Impr...

Oncology

Nanoparticle accumulation and penetration in 3D tumor models: the effect of size, shape, and surface charge

Frontiers in Cell and Developmental Biology · 2025 · Cybulski, Pierre, et al

Published in Frontiers in Cell and Developmental Biology (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Cybu...

Oncology

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology · 2025 · Outla, Zuzana, et al

Published in Molecular Oncology (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Outla, Zuzana, et al. Plecsta...

Oncology

Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments

STAR Protocols · 2025 · León, Sergio, et al

Published in STAR Protocols (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: León, Sergio, et al. Protocol to ...

Oncology

Sonidegib Inhibits the Adhesion of Acute Myeloid Leukemia to the Bone Marrow in Hypoxia: An Optical Tweezer Study

Biomedicines · 2025 · Gdesz-Birula, Katarzyna, et al

Published in Biomedicines (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Gdesz-Birula, Katarzyna, et al. Son...

Oncology

Targeted editing of CCL5 with CRISPR-Cas9 nanoparticles enhances breast cancer immunotherapy

Apoptosis · 2025 · Yan, Wei, et al

Published in Apoptosis (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Yan, Wei, et al. Targeted editing of C...

Oncology

TEAD inhibition alters the lung immune microenvironment and attenuates metastasis. bioRxiv (2025): 2025-02

bioRxiv · 2025 · Sharif, Ghada M., et al

Published in a peer-reviewed journal (2025), this study utilized 3D Petri Dish® micro-molds to generate uniform microtissues for investigating 'tead inhibition alters the lung immu...

Oncology

The HNRNPC/CELF2 signaling pathway drives glycolytic reprogramming and mitochondrial dysfunction in drug-resistant acute myeloid leukemia

Cell & Bioscience · 2025 · Ma, Xiang, et al

Published in Cell & Bioscience (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Ma, Xiang, et al. The HNRNPC/C...

Oncology

The MYC/TXNIP axis mediates NCL-Suppressed CD8+T cell immune response in lung adenocarcinoma

Molecular Medicine · 2025 · Xiao, Dan, et al

Published in Molecular Medicine (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Xiao, Dan, et al. The MYC/TXN...

Oncology

Thermoresponsive nanoparticles for targeted and controlled delivery of doxorubicin in triple negative breast cancer: a 2D and 3D in vitro evaluation

Drug Delivery and Translational Research · 2025 · Ribeiro, Tiago P., et al

Published in Drug Delivery and Translational Research (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Ribeiro...

Oncology

Unveiling the key mechanisms of FOLR2+ macrophage-mediated antitumor immunity in breast cancer using integrated single-cell RNA sequencing and bulk RNA sequencing

Breast Cancer Research · 2025 · Wu, Sixuan, et al

Published in Breast Cancer Research (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Wu, Sixuan, et al. Unveil...

Oncology

Zinc complex with quinoline-based thiazolyl-hydrazone targeting DNA replication in cancer cells

Scientific Reports · 2025 · Maciejewska, Natalia, et al

Published in Scientific Reports (2025), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Maciejewska, Natalia, et al. ...

Oncology

A study with cancer stem cells and three-dimensional tumoroids: investigation of the combined effects of 5-fluorouracil and doxorubicin in breast cancer

Medical Oncology · 2024 · Erden Tayhan, Seçil

Published in Medical Oncology (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Erden Tayhan, Seçil. A study wi...

Oncology

A549 Alveolar Carcinoma Spheroids as a Cytotoxicity Platform for Carboxyl‐ and Amine‐Polyethylene Glycol Gold Nanoparticles

Pharmacology Research & Perspectives · 2024 · Petzer, Melissa, et al

Published in Pharmacology Research & Perspectives (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Petzer, Mel...

Oncology

Advanced Microfluidic Platform for Tumor Spheroid Formation and Cultivation Fabricated from OSTE+ Polymer

BioChip Journal · 2024 · Panuška, Petr, et al

Published in BioChip Journal (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Panuška, Petr, et al. Advanced M...

Oncology

Blockage of αvβ3 integrin in 3D culture of triple-negative breast cancer and endothelial cells inhibits migration and discourages endothelial-to-mesenchymal plasticity

Biochemistry and Biophysics Reports · 2024 · Casali, Bruna Carla, et al

Published in Biochemistry and Biophysics Reports (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Casali, Brun...

Oncology

Delivery of IL2RG mRNA via nanoparticles to enhance CD8+ T cell promotes anti-tumor effects against late-stage triple-negative breast cancer

Cancer Nanotechnology · 2024 · Li, Ying, et al

Published in Cancer Nanotechnology (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Li, Ying, et al. Delivery ...

Oncology

Discovery of Potent Isoquinolinequinone N -Oxides to Overcome Cancer Multidrug Resistance

Journal of Medicinal Chemistry · 2024 · Kruschel, Ryan D., et al

Published in Journal of Medicinal Chemistry (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Kruschel, Ryan D....

Oncology

Involvement of Kindlin-1 in cutaneous squamous cell carcinoma

Oncogenesis · 2024 · Carrasco, Giovana, et al

Published in Oncogenesis (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Carrasco, Giovana, et al. Involvemen...

Oncology

KRAS silencing alters chromatin physical organization and transcriptional activity in colorectal cancer cells

Research Square · 2024 · Martins, Flávia, et al

Published in Research Square (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Martins, Flávia, et al. KRAS sil...

Oncology

MAPKAP1 orchestrates macrophage polarization and lipid metabolism in fatty liver-enhanced colorectal cancer

Translational Oncology · 2024 · Huang, Bo, et al

Published in Translational Oncology (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Huang, Bo, et al. MAPKAP1...

Oncology

Microtubule‐associated NAV3 regulates invasive phenotypes in glioblastoma cells

Brain Pathology · 2024 · Škarková, Aneta, et al

Published in Brain Pathology (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Škarková, Aneta, et al. Microtub...

Oncology

Novel combination therapy using recombinant oncolytic adenovirus silk hydrogel and PD-L1 inhibitor for bladder cancer treatment

Journal of Nanobiotechnology · 2024 · Zhang, Wenqiang, et al

Published in Journal of Nanobiotechnology (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Zhang, Wenqiang, et...

Oncology

Particle uptake in cancer cells can predict malignancy and drug resistance using machine learning

Science Advances · 2024 · Goldstein, Yoel, et al

Published in Science Advances (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Goldstein, Yoel, et al. Particl...

Oncology

Patient‐Derived Melanoma Immune‐Tumoroids as a Platform for Precise High throughput Drug Screening

Advanced Science · 2024 · Viegas, Juliana, et al

Published in Advanced Science (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Viegas, Juliana, et al. Patient...

Oncology

Patterned PVA Hydrogels with 3D Petri Dish® Micro-Molds of Varying Topography for Spheroid Formation of HeLa Cancer Cells: In Vitro Assessment

Gels · 2024 · Moreno Valtierra, Maira, et al

Published in Gels (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Moreno Valtierra, Maira, et al. Patterned P...

Oncology

Phenylthiazolidin-4-one piperazine Conjugates: Design, Synthesis, anticancer and antimicrobial studies

Results in Chemistry · 2024 · Singh, Dalbir, et al

Published in Results in Chemistry (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Singh, Dalbir, et al. Pheny...

Oncology

Protocol for formation, staining, and imaging of 3D breast cancer models using MicroTissues mold systems

STAR Protocols · 2024 · Haspels, Ben, et al

Published in STAR Protocols (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Haspels, Ben, et al. Protocol for...

Oncology

Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models

STAR Protocols · 2024 · Labrosse, Kathrin B., et al

Published in STAR Protocols (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Labrosse, Kathrin B., et al. Prot...

Oncology

Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma restrict CD8+ T cell activation and limit responsiveness to immunotherapy in mice

Nature Communications · 2024 · Assouline, Benjamin, et al

Research published in Nature Communications (2024) used 3D Petri Dish® tumor spheroids to discover that senescent cancer-associated fibroblasts (CAFs) suppress T cell activation in...

Oncology

Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety

RSC Medicinal Chemistry · 2024 · Formánek, Bedřich, et al

Published in RSC Medicinal Chemistry (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Formánek, Bedřich, et al...

Oncology

Ultrastable Iodinated Oil-Based Pickering Emulsion Enables Locoregional Sustained Codelivery of Hypoxia Inducible Factor-1 Inhibitor and Anticancer Drugs for Tumor Combination Chemotherapy

ACS Biomaterials Science & Engineering · 2024 · Li, Zhihua, et al

Published in ACS Biomaterials Science & Engineering (2024), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Li, Zhihu...

Oncology

A fully 3D-printed versatile tumor-on-a-chip allows multi-drug screening and correlation with clinical outcomes for personalized medicine

Communications Biology · 2023 · Steinberg, Eliana, et al

Published in Communications Biology (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Steinberg, Eliana, et al....

Oncology

An Optimized Method to Culture Human Primary Lung Tumor Cell Spheroids

Cancers · 2023 · Mueggler, Amanda, et al

Published in Cancers (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Mueggler, Amanda, et al. An Optimized Me...

Oncology

Analyzing force measurements of multi-cellular clusters comprising indeterminate geometries

Biomechanics and Modeling in Mechanobiology · 2023 · Brill-Karniely, Yifat, et al

Published in Biomechanics and Modeling in Mechanobiology (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Bril...

Oncology

Biodistribution and toxicity assessment of methoxyphenyl phosphonium carbosilane dendrimers in 2D and 3D cell cultures of human cancer cells and zebrafish embryos

Scientific Reports · 2023 · Žmudová, Zuzana, et al

Published in Scientific Reports (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Žmudová, Zuzana, et al. Biodi...

Oncology

Carbonic Anhydrase Inhibitors Induce Ferroptosis through Inhibition of AKT/FTH1 Signaling in Ewing Sarcoma Tumor Cells

Cancers · 2023 · Fayzullina, Darya, et al

Published in Cancers (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Fayzullina, Darya, et al. Carbonic Anhyd...

Oncology

Differential Protein and Glycan Packaging into Extracellular Vesicles in Response to 3D Gastric Cancer Cellular Organization

Advanced Science · 2023 · Martins, Álvaro M., et al

Published in Advanced Science (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Martins, Álvaro M., et al. Diff...

Oncology

Ex Vivo Model of Neuroblastoma Plasticity

Cancers · 2023 · Schäfer, Paula, et al

Published in Cancers (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Schäfer, Paula, et al. Ex Vivo Model of ...

Oncology

Inhibition of TGF-β signaling, invasion, and growth of cutaneous squamous cell carcinoma by PLX8394

Oncogene · 2023 · Siljamäki, Elina, et al

Published in Oncogene (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Siljamäki, Elina, et al. Inhibition of ...

Oncology

Mimicking 3D breast tumor-stromal interactions to screen novel cancer therapeutics

European Journal of Pharmaceutical Sciences · 2023 · Domingues, Mariana, et al

Published in European Journal of Pharmaceutical Sciences (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Domi...

Oncology

Multicellular Quadruple Colorectal Cancer Spheroids as an In Vitro Tool for Antiangiogenic Potential Evaluation of Nanoparticles

Advanced Therapeutics · 2023 · Carvalho, Suzana, et al

Published in Advanced Therapeutics (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Carvalho, Suzana, et al. M...

Oncology

Novel PD-L1- and collagen-expressing patient-derived cell line of undifferentiated pleomorphic sarcoma (JBT19) as a model for cancer immunotherapy

Scientific Reports · 2023 · Taborska, Pavla, et al

Published in Scientific Reports (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Taborska, Pavla, et al. Novel...

Oncology

Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer

International Journal of Pharmaceutics · 2023 · Nascimento, Camila, et al

Published in International Journal of Pharmaceutics (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Nasciment...

Oncology

Selenylated Imidazo [1,2-a]pyridine Induces Apoptosis and Oxidative Stress in 2D and 3D Models of Colon Cancer Cells

Pharmaceuticals · 2023 · Gomes, Giovana Bicudo, et al

Published in Pharmaceuticals (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Gomes, Giovana Bicudo, et al. Se...

Oncology

The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells

Bioscience Reports · 2023 · Küster, Lukas, et al

Published in Bioscience Reports (2023), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Küster, Lukas, et al. The act...

Oncology

Three-dimensional heterotypic colorectal cancer spheroid models for evaluation of drug response

Frontiers in Oncology · 2023 · Yau, Jia Ning Nicolette, et al

Published in Frontiers in Oncology (2023), this publication cites the 3D Petri Dish® micro-mold system rather than reporting its own experimental use of it. Full citation: Yau, Jia...

Oncology

Development and Characterization of 3D Hybrid Spheroids for the Investigation of the Crosstalk Between B-Cell Non-Hodgkin Lymphomas and Mesenchymal Stromal Cells

OncoTargets and Therapy · 2022 · Duś-Szachniewicz, Kamila, et al

Published in OncoTargets and Therapy (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Duś-Szachniewicz, Kamila...

Oncology

Disruption of Redox Homeostasis by Alterations in Nitric Oxide Synthase Activity and Tetrahydrobiopterin along with Melanoma Progression

International Journal of Molecular Sciences · 2022 · Soares, Jaqueline Pereira Moura, et al

Published in International Journal of Molecular Sciences (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Soar...

Oncology

Effect of Compressive Stress in Tumor Microenvironment on Malignant Tumor Spheroid Invasion Process

International Journal of Molecular Sciences · 2022 · Nishi, Ryota, et al

Published in International Journal of Molecular Sciences (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Nish...

Oncology

Impaired CXCL12 signaling contributes to resistance of pancreatic cancer subpopulations to T cell-mediated cytotoxicity

OncoImmunology · 2022 · Lin, Yuan-Na, et al

Published in OncoImmunology (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Lin, Yuan-Na, et al. Impaired CXC...

Oncology

Inflammation-related citrullination of matrisome proteins in human cancer

Frontiers in Oncology · 2022 · Rappu, Pekka, et al

Published in Frontiers in Oncology (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Rappu, Pekka, et al. Infla...

Oncology

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids

Cells · 2022 · Białkowska, Kamila, et al

Published in Cells (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Białkowska, Kamila, et al. Interaction of ...

Oncology

Lipidomic comparison of 2D and 3D colon cancer cell culture models

Journal of Mass Spectrometry · 2022 · Tobias, Fernando, et al

Published in Journal of Mass Spectrometry (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Tobias, Fernando, e...

Oncology

Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis

Bioactive Materials · 2022 · Guo, Yaru, et al

Published in Bioactive Materials (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Guo, Yaru, et al. Matrix sti...

Oncology

Newly synthesized methionine aminopeptidase 2 inhibitor hinders tumor growth

Drug Delivery and Translational Research · 2022 · Esa, Rawnaq, et al

Published in Drug Delivery and Translational Research (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Esa, Ra...

Oncology

Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer

Journal of Controlled Release · 2022 · Almeida, Andreia, et al

Published in Journal of Controlled Release (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Almeida, Andreia, ...

Oncology

Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet

Cells · 2022 · De Burghgrave, Marine, et al

Published in Cells (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: De Burghgrave, Marine, et al. Pancreatic I...

Oncology

PBRM1 is a vulnerability in ARID1A deficient multicellular tumor spheroids

bioRxiv · 2022 · Chakravarty, V., et al

Published in bioRxiv (2022) (2022), this study utilized 3D Petri Dish® micro-molds to generate uniform microtissues for investigating pbrmi is a vulnerability in arid i a deficient...

Oncology

Poly(2-Ethyl-2-Oxazoline)–IR780 Conjugate Nanoparticles for Breast Cancer Phototherapy

Nanomedicine · 2022 · Alves, Cátia G, et al

Published in Nanomedicine (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Alves, Cátia G, et al. Poly(2-Ethyl...

Oncology

Radiodynamic Therapy with Acridine Orange Is an Effective Treatment for Bone Metastases

Biomedicines · 2022 · Di Pompo, Gemma, et al

Published in Biomedicines (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Di Pompo, Gemma, et al. Radiodynami...

Oncology

The drug-induced phenotypic landscape of colorectal cancer organoids

Nature Communications · 2022 · Betge, Johannes, et al

Published in Nature Communications (2022), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Betge, Johannes, et al. Th...

Oncology

3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs

Cancers · 2021 · Barbosa, Mélanie A. G., et al

Published in Cancers (2021), this publication cites the 3D Petri Dish® micro-mold system rather than reporting its own experimental use of it. Full citation: Barbosa, Mélanie A. G....

Oncology

Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis

Scientific Reports · 2021 · Berta, Judit, et al

Published in Scientific Reports (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Berta, Judit, et al. Apelin p...

Oncology

Lung carcinoma spheroids embedded in a microfluidic platform

Cytotechnology · 2021 · Yildiz-Ozturk, Ece, et al

Published in Cytotechnology (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Yildiz-Ozturk, Ece, et al. Lung c...

Oncology

Mammary Tumor Organoid Culture in Non‐Adhesive Alginate for Luminal Mechanics and High‐Throughput Drug Screening

Advanced Science · 2021 · Fang, Guocheng, et al

Published in Advanced Science (2021), this publication cites the 3D Petri Dish® micro-mold system rather than reporting its own experimental use of it. Full citation: Fang, Guochen...

Oncology

Poly(2-ethyl-2-oxazoline) functionalized reduced graphene oxide: Optimization of the reduction process using dopamine and application in cancer photothermal therapy

Materials Science and Engineering: C · 2021 · Lima-Sousa, Rita, et al

Published in Materials Science and Engineering: C (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Lima-Sousa,...

Oncology

Preparation of Ethanol Extract of Propolis Loaded Niosome Formulation and Evaluation of Effects on Different Cancer Cell Lines

Nutrition and Cancer · 2021 · Cetin, Emel Oyku, et al

Published in Nutrition and Cancer (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Cetin, Emel Oyku, et al. Pr...

Oncology

Suppressive Effects of Anisomycin on the Proliferation of B16 Mouse Melanoma CellsIn Vitro

Anticancer Research · 2021 · USHIJIMA, HIRONORI, et al

Published in Anticancer Research (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: USHIJIMA, HIRONORI, et al. S...

Oncology

The matrix-dependent 3D spheroid model of the migration of non-small cell lung cancer: a step towards a rapid automated screening

Frontiers in Molecular Biosciences · 2021 · Shabalina, Evgenya Y., et al

Published in Frontiers in Molecular Biosciences (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Shabalina, Ev...

Oncology

TLR4-Mediated Recognition of Mouse Polyomavirus Promotes Cancer-Associated Fibroblast-Like Phenotype and Cell Invasiveness

Cancers · 2021 · Janovec, Vaclav, et al

Published in Cancers (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Janovec, Vaclav, et al. TLR4-Mediated Re...

Oncology

Understanding the Biological Basis of Glioblastoma Patient-derived Spheroids

Anticancer Research · 2021 · TURNOVCOVA, KAROLÍNA, et al

Published in Anticancer Research (2021), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: TURNOVCOVA, KAROLÍNA, et al....

Oncology

Analysis of the Effect of Increased α2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib

International Journal of Molecular Sciences · 2020 · Balmaña, Meritxell, et al

Published in International Journal of Molecular Sciences (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Balm...

Oncology

Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models

Biotechnology Journal · 2020 · Mó, Inês, et al

Published in Biotechnology Journal (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Mó, Inês, et al. Assessing...

Oncology

Colorectal cancer triple co-culture spheroid model to assess the biocompatibility and anticancer properties of polymeric nanoparticles

Journal of Controlled Release · 2020 · Bauleth-Ramos, Tomás, et al

Published in Journal of Controlled Release (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Bauleth-Ramos, Tom...

Oncology

High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy

Frontiers in Molecular Biosciences · 2020 · Edwards, Steven J., et al

Published in Frontiers in Molecular Biosciences (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Edwards, Stev...

Oncology

IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma

Journal for ImmunoTherapy of Cancer · 2020 · Zhang, Wenjie, et al

Published in Journal for ImmunoTherapy of Cancer (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Zhang, Wenji...

Oncology

Increased Level of Long Non-Coding RNA MALAT1 Is a Common Feature of Amoeboid Invasion

Cancers · 2020 · Merta, Ladislav, et al

Published in Cancers (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Merta, Ladislav, et al. Increased Level ...

Oncology

Integrin a2b1 targeted self-assembled nanocarrier for tumor bioimaging

ACS Applied Bio Materials · 2020 · Fluksman, A., et al

Published in ACS Applied Bio Materials (2020), this study utilized 3D Petri Dish® micro-molds to generate uniform microtissues for investigating integrin a2b1 targeted self-assembl...

Oncology

Monitoring Cancer Cell Invasion and T-Cell Cytotoxicity in 3D Culture

Journal of Visualized Experiments · 2020 · Lin, Yuan-Na, et al

Published in Journal of Visualized Experiments (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Lin, Yuan-Na, ...

Oncology

Rapid Clearing for High Resolution 3D Imaging of Ex Vivo Pancreatic Cancer Spheroids

International Journal of Molecular Sciences · 2020 · Steinberg, Eliana, et al

Published in International Journal of Molecular Sciences (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Stei...

Oncology

Sample preparation strategies for high‐throughput mass spectrometry imaging of primary tumor organoids

Journal of Mass Spectrometry · 2020 · Johnson, Jillian, et al

Published in Journal of Mass Spectrometry (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Johnson, Jillian, e...

Oncology

Sustained Inflammatory Signalling through Stat1/Stat2/IRF9 Is Associated with Amoeboid Phenotype of Melanoma Cells

Cancers · 2020 · Gandalovičová, Aneta, et al

Published in Cancers (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Gandalovičová, Aneta, et al. Sustained I...

Oncology

Targeting the Tumor Core: Hypoxia-Responsive Nanoparticles for the Delivery of Chemotherapy to Pancreatic Tumors

Molecular Pharmaceutics · 2020 · Confeld, Matthew I., et al

Published in Molecular Pharmaceutics (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Confeld, Matthew I., et ...

Oncology

Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability

Science Advances · 2020 · Brill-Karniely, Yifat, et al

Published in Science Advances (2020), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Brill-Karniely, Yifat, et al. T...

Oncology

A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells

BMC Cancer · 2019 · Klicks, Julia, et al

Published in BMC Cancer (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Klicks, Julia, et al. A novel spheroi...

Oncology

Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells

Cells · 2019 · Szeder, Bálint, et al

Published in Cells (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Szeder, Bálint, et al. Absence of the Tks4...

Oncology

Chemically defined conditions for long-term maintenance of pancreatic progenitors derived from human induced pluripotent stem cells

Scientific Reports · 2019 · Konagaya, Shuhei, et al

Published in Scientific Reports (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Konagaya, Shuhei, et al. Chem...

Oncology

Hyaluronic acid functionalized nanoparticles loaded with IR780 and DOX for cancer chemo-photothermal therapy

European Journal of Pharmaceutics and Biopharmaceutics · 2019 · Alves, Cátia G., et al

Published in European Journal of Pharmaceutics and Biopharmaceutics (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full cit...

Oncology

Integration of hyper-compliant microparticles into a 3D melanoma tumor model

Journal of Biomechanics · 2019 · Shah, Manisha K., et al

Published in Journal of Biomechanics (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Shah, Manisha K., et al....

Oncology

MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors

Nature Communications · 2019 · Chen, Xinyue, et al

Published in Nature Communications (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Chen, Xinyue, et al. MLL-A...

Oncology

Scaffold-Free Endometrial Organoids Respond to Excess Androgens Associated With Polycystic Ovarian Syndrome

The Journal of Clinical Endocrinology & Metabolism · 2019 · Wiwatpanit, Teerawat, et al

Published in The Journal of Clinical Endocrinology & Metabolism (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citatio...

Oncology

Acoustic formation of multicellular tumor spheroids enabling on-chip functional and structural imaging

Lab on a Chip · 2018 · Olofsson, K., et al

Published in Lab on a Chip (2018), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Olofsson, K., et al. Acoustic form...

Oncology

Enrichment of cancer stem cells by agarose multi-well dishes and 3D spheroid culture

Cell and Tissue Research · 2018 · Guo, Xiaoling, et al

Published in Cell and Tissue Research (2018), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Guo, Xiaoling, et al. E...

Oncology

Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells

Oncotarget · 2018 · Ojalill, Marjaana, et al

Published in Oncotarget (2018), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Ojalill, Marjaana, et al. Integrin α2...

Oncology

Multicellular Human Gastric Cancer Spheroids Mimic the Glycosylation Phenotype of Gastric Carcinomas

Molecules · 2018 · Balmaña, Meritxell, et al

Published in Molecules (2018), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Balmaña, Meritxell, et al. Multicellul...

Oncology

The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis

The Prostate · 2018 · Ojalill, Marjaana, et al

Published in The Prostate (2018), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Ojalill, Marjaana, et al. The compo...

Oncology

Coadministration of a tumor‐penetrating peptide improves the therapeutic efficacy of paclitaxel in a novel air‐grown lung cancer 3D spheroid model

International Journal of Cancer · 2017 · Gupta, Sweta K., et al

Published in International Journal of Cancer (2017), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Gupta, Sweta K.,...

Oncology

The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion

Nature Communications · 2017 · Jiang, Runqiu, et al

Published in Nature Communications (2017), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Jiang, Runqiu, et al. The ...

Oncology

Tumor cells and their crosstalk with endothelial cells in 3D spheroids

Scientific Reports · 2017 · Shoval, Hila, et al

This study by Shoval, H. et al was published in 2017. It utilized Microtissues 3D Petri Dish® micro-molds for 3D cell culture, contributing to advances in oncology research.

Oncology

Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell

Biochemical and Biophysical Research Communications · 2016 · Ushijima, Hironori, et al

Published in Biochemical and Biophysical Research Communications (2016), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citati...

Oncology

Cisplatin Resistant Spheroids Model Clinically Relevant Survival Mechanisms in Ovarian Tumors

PLOS ONE · 2016 · Chowanadisai, Winyoo, et al

Published in PLOS ONE (2016), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Chowanadisai, Winyoo, et al. Cisplatin ...

Oncology

Comparison of KP1019 and NAMI-A in tumour-mimetic environments

Metallomics · 2016 · Gransbury, Gemma K., et al

This study by K. Gransbury, G. et al was published in 2016. It utilized Microtissues 3D Petri Dish® micro-molds for 3D cell culture, contributing to advances in other research.

Oncology

Reproducible preparation of spheroids of pancreatic hormone positive cells from human iPS cells: An in vitro study

Biochimica et Biophysica Acta (BBA) - General Subjects · 2016 · Konagaya, Shuhei, et al

Published in Biochimica et Biophysica Acta (BBA) - General Subjects (2016), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full cit...

Oncology

Architecture of Chimeric Spheroids Controls Drug Transport

Cancer Microenvironment · 2015 · Curran, Sean, et al

Published in Cancer Microenvironment (2015), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Curran, Sean, et al. Arc...

Oncology

Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin

Journal of Controlled Release · 2015 · Gaspar, Vítor M., et al

Published in Journal of Controlled Release (2015), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Gaspar, Vítor M., ...

Oncology

Chimeric Virus-Like Particles Made Using GAG and M1 Capsid Proteins Providing Dual Drug Delivery and Vaccination Platform

Molecular Pharmaceutics · 2015 · Deo, Vipin K., et al

Published in Molecular Pharmaceutics (2015), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Deo, Vipin K., et al. Ch...

Oncology

MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels

PLOS ONE · 2015 · Vantangoli, Marguerite M., et al

Published in PLOS ONE (2015), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Vantangoli, Marguerite M., et al. MCF-7...

Oncology

A Model for Targeting Colon Carcinoma Cells Using Single-Chain Variable Fragments Anchored on Virus-Like Particles via Glycosyl Phosphatidylinositol Anchor

Pharmaceutical Research · 2014 · Deo, Vipin Kumar, et al

Published in Pharmaceutical Research (2014), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Deo, Vipin Kumar, et al....

Oncology

Identification of Ovarian Cancer Metastatic miRNAs

PLoS ONE · 2013 · Vang, Souriya, et al

Published in PLoS ONE (2013), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Vang, Souriya, et al. Identification of...

Oncology

Penetration of Endothelial Cell Coated Multicellular Tumor Spheroids by Iron Oxide Nanoparticles

Theranostics · 2012 · Ho, Don N., et al

Published in Theranostics (2012), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Ho, Don N., et al. Penetration of E...

Oncology

Bcl-2 Family Proteins Contribute to Apoptotic Resistance in Lung Cancer Multicellular Spheroids

American Journal of Respiratory Cell and Molecular Biology · 2009 · Yang, Tsung-Ming, et al

This study by Yang, T-M, et al was published in 2009. It utilized Microtissues 3D Petri Dish® micro-molds for 3D cell culture, contributing to advances in oncology research.

Oncology

Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids

Journal of Biological Chemistry · 2008 · Barbone, Dario, et al

This study by Barbone, D., et al was published in Chem, 2008. It utilized Microtissues 3D Petri Dish® micro-molds for 3D cell culture, contributing to advances in oncology research...

Frequently asked questions

Why use tumor spheroids instead of 2D cancer cell culture?

Spheroids restore the 3D architecture, cell-cell contacts, and gradients that flat culture lacks, which is why they are widely used as more physiologically relevant tumor models in drug-response and invasion studies. The publications below show how labs apply them.

How uniform are the spheroids?

Each recess in the cast agarose gel forms one spheroid, and size is set by the number of cells seeded — so a single mold yields an array of spheroids of matched size, suitable for consistent dosing and imaging.

Can I co-culture tumor cells with other cell types?

Yes. Mixed microtissues have been formed from two and even three cell types mixed at a chosen ratio before seeding — the studies below include tumor-stroma and tumor-immune co-culture models.

More questions? See the full FAQ, learn what a microtissue is, or read the guide to imaging 3D microtissues.