Microtissues®

Summary

Published in World Journal of Stem Cells (2022), this publication cites the 3D Petri Dish® micro-mold system rather than reporting its own experimental use of it. Full citation: Yuan, Sheng-Meng, et al. Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications

🔬 Stem Cells

Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications

World Journal of Stem Cells 2022 Yuan, Sheng-Meng, et al
Cite as: Yuan, Sheng-Meng, et al. Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications. World Journal of Stem Cells (2022). doi:10.4252/wjsc.v14.i7.435 doi.org/10.4252/wjsc.v14.i7.435

Research Overview

Dental pulp stem cells and their derivatives have shown beneficial effects across disease models in many tissues and organs, making them strong candidates for stem-cell-based regeneration. This review provides an overview of their potential applications in regenerative medicine.

It describes how cells isolated from donors of different ages and health conditions compare, introduces the methods used to administer them therapeutically — single injections, transplantation with a supporting material, cell sheets, or cell spheroids — and summarizes the mechanisms thought to underlie their regenerative effect.

Key Discoveries

  • Reviews dental pulp stem cells and derivatives across regenerative applications
  • Compares cells from donors of differing age and health status
  • Covers delivery formats: injection, supported transplantation, cell sheets, and spheroids