Summary
This study by Barbone, D., et al was published in Chem, 2008. It utilized Microtissues 3D Petri Dish® micro-molds for 3D cell culture, contributing to advances in oncology research.
🧬 Oncology
V.C. mTOR Contributes to the Acquired Multicellular Apoptotic Resistance of Huma
Chem, 2008 2008 Barbone, D., et al
Cite as: Citation:Barbone, D., et al. V.C. mTOR Contributes to the Acquired Multicellular Apoptotic Resistance of Human Malignant Mesothelioma Spheroids. J. Biol. Chem. 283: 13021-13030, (2008) doi.org/10.1074/jbc.M709698200
Research Overview
This publication by Barbone, D., et al represents important research in the field of oncology. Published in Chem, 2008, this work employed 3D Petri Dish® micro-mold technology from Microtissues to create uniform, reproducible 3D microtissues for their experimental studies.
Key Discoveries
- Utilized Microtissues 3D Petri Dish® micro-molds for reproducible 3D spheroid formation
- Enabled physiologically relevant cell-cell interactions in a controlled 3D environment
- Supported the study of complex biological processes that cannot be replicated in traditional 2D culture
3D Petri Dish® Application
3D Petri Dish® Application
- Non-adhesive hydrogel micro-molds promoted self-assembly of cells into 3D spheroids:
- Uniform microtissue size ensured experimental reproducibility:
- Compatible with standard cell culture workflows and imaging techniques: