Summary
Published in Inter J of Pharmaceutics (2023) (2023), this study utilized 3D Petri Dish® micro-molds to generate uniform microtissues for investigating reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer. The research demonstrates the value of standardized 3D cell culture models in advancing our understanding of this field.
🧬 Oncology
Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer
Inter J of Pharmaceutics (2023), 2023 · Nascimento, C. et al 2023 Nascimento, C. et al
Cite as: Citation: Nascimento, C. et al. Reprogramming of tumor-associated macrophages by polyaniline-coated iron oxide nanoparticles applied to treatment of breast cancer. Inter J of Pharmaceutics (2023) 2023 doi.org/10.1016/j.ijpharm.2023.122866
3D Petri Dish® Application
3D Petri Dish®
Frequently Asked Questions
Why use tumor spheroids for cancer research?
Tumor spheroids develop oxygen and nutrient gradients similar to solid tumors, including a hypoxic core. This allows researchers to evaluate how well therapeutic agents penetrate into the tumor and perform under realistic conditions that cannot be replicated in flat cell cultures.