Summary
Published in Archives of Toxicology (2019), this peer-reviewed study used 3D Petri Dish® micro-molds to form scaffold-free 3D microtissues. Full citation: Krewski, D., et al. Toxicity testing in the 21st century: progress in the past decade and future perspectives
Toxicity testing in the 21st century: progress in the past decade and future perspectives
Research Overview
Biological advances have driven an ongoing paradigm shift in toxicity testing toward high-throughput in vitro screening and in silico methods for assessing health risks of environmental agents.
This review examines progress against the vision set out by the US National Research Council in its 2007 report on Toxicity Testing in the 21st Century, over the decade that followed. It also documents parallel advances in exposure assessment, including computational approaches and high-throughput exposomics, and sets out a vision for the next generation of risk science.
Key Discoveries
- Assesses a decade of progress against the NRC's Toxicity Testing in the 21st Century vision
- Documents parallel advances in computational exposure assessment and high-throughput exposomics
- Outlines the next generation of risk science integrating in vitro and in silico methods
